'Do Not Make Success Inconsequential'

This gem is from Vinod Khosla: It is a very good idea to place huge bets on projects, as long as the successful scenario is 'worth it'. The mistake that most VCs and entrepreneurs do, is that they eliminate risk so much, that in the process, they reduce the 'impact' of the project. This reduces the consequences of success greatly - in other words, success becomes inconsequential. Not a preferred outcome.

In executing a black swan opportunity, do not turn it into grey or white. Sums it up.